LLMs generate content. LQMs generate results.

Large Quantitative Models (LQMs) are driven by real world data and comprise different architecture than LLMs.

LLM + LQM for Scale and Impact.

Prompt

Users prompt for a quantitative result which needs real world data and analysis.

LLMs are the interface, but the real world answer must come from a real world model.

Models

Specified Problem

LLM

User Interface, RAG, and AI Agent

Quantitative Output

Specified Problem

Quantitative Output

LQM Modules

Quantitative Models

Physics Models

Simulations

Real World Insights

No Hallucinations

Chemistry

Physics

Biology

Large Quantitative Models for the real world.

SandboxAQ connects AI and Quantum techniques for business breakthroughs across pharma, energy, defense, and other high-impact markets.

We’re not just building smarter models. We’re building AI that understands the physical world. This is Quantitative AI.

AI Agents at Scale: Why Security and Control Matter Now | Jack Hidary on CNBC

AQ Affinity, AI for the Physical World, and Post-Quantum Security | Jack Hidary on Fox Business

2026 Will Be an Explosive Year for AI | SandboxAQ CEO Jack Hidary

Preparing for Q-Day : How Bahrain Is Securing Its Digital Economy with SandboxAQ | CNBC

Davos Takeaway: Why India’s AI Push Is Shifting From Promise to Power

AI or Die Moment for Companies and Governments: India Positioned to Benefit, says Global Expert

SandboxAQ’s AQAffinity Changes the Workflow for Drug Affinity Prediction

GPS Jamming and Cybersecurity Loom Large at Davos

Beyond the Hype: What I’m Looking for at Davos 2026

AQAffinity: Open-Source Structure-to-Affinity Built on OpenFold3 by SandboxAQ

Large Quantitative Models: How AI is Accelerating Drug Discovery

We're Running Low on Data to Train AI. The Good News is There's a Fix for That

Where LQMs create value.

Drug discovery

Accelerating molecular design and reducing failure rates.

Learn More

Chemicals & materials

Predicting properties at the atomic level to unlock new compounds.

Learn More

Get in Touch

Talk with us

Datasets, case studies, and validated results across industries.

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Why Visionaries Are Partnering with SandboxAQ

"I invested in SandboxAQ because of their industry-leading approach to quantitative AI. While LLMs are very helpful tools for consumers, it is quantitative AI that will define work in large sectors of the economy including biopharma, chemicals and financial services. I am impressed by the technical depth of Jack and his team and am excited to support their work. SandboxAQ has emerged as a leader in novel applications of AI that solve the most pressing challenges in the world and their technical success is impressive."

– Yann LeCun, leading AI scientist, one of three Turing Award winners for deep learning

"We are proud investors in SandboxAQ. We believe deeply in Jack and his team, and are committed to their vision to advance technology and transform industries through their leadership in the next wave of AI and its connection with quantum technologies. We support SandboxAQ’s portfolio approach to developing novel products in cybersecurity, navigation, and AI simulation, and are seeing their successes reflected in customer engagement. Jack and the team combine vision and execution and we are excited to grow with him and the company."

– USIT Investment Fund

"I am very excited to see the continued success of SandboxAQ. As part of the spinout team and now as a senior advisor, it is very gratifying to see all the hard work translate into real impact in the world. SandboxAQ’s combination of AI and quantum tools is changing the game in sectors such as biopharma, materials and cyber. Jack and the team are leading the company to new achievements and I look forward to continued involvement with the company as it grows further."

– Jen Sovada, Senior Advisor, SandboxAQ

“We’re proud to be backing SandboxAQ and its impressive accomplishments. Jack and his team have surpassed the expectations they set when we invested and we look forward to their continued success. Jack is a world-class leader who uniquely combines technical and business skills to execute on this vision with his team. SandboxAQ is the pacesetter in quantitative AI which has impact in multiple large sectors of the economy.”

– Jim Breyer, CEO, Breyer Capital

“It has been great to follow and to help drive the progress of SandboxAQ and its large quantitative models, enabled by a deeply technical team. The traction with large enterprise customers speaks for itself. As a senior advisor and former senior executive, I look forward to the continued scaling and impact of SandboxAQ.”

– Chris Hume, Senior Advisor, SandboxAQ

Trusted by Leading Global Enterprises

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Explore how LQMs could transform your enterprise.

See how LQMs deliver measurable outcomes across drug discovery, materials, finance, navigation, and cybersecurity.

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